MICELLAR ELECTROKINETIC CHROMATOGRAPHY AS A FAST SCREENING METHOD FORTHE DETERMINATION OF THE DOPING AGENTS FUROSEMIDE AND PIRETANIDE IN URINE

Authors
LALLJIE SPD BARROSO MB STEENACKERS D ALONSO RM JIMENEZ RM SANDRA P
Citation
Spd. Lalljie et al., MICELLAR ELECTROKINETIC CHROMATOGRAPHY AS A FAST SCREENING METHOD FORTHE DETERMINATION OF THE DOPING AGENTS FUROSEMIDE AND PIRETANIDE IN URINE, Journal of chromatography B. Biomedical sciences and applications, 688(1), 1997, pp. 71-78
Citations number
31
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography B. Biomedical sciences and applications → ACNP
ISSN journal
13872273
Volume
688
Issue
1
Year of publication
1997
Pages
71 - 78
Database
ISI
SICI code
0378-4347(1997)688:1<71:MECAAF>2.0.ZU;2-Q
Abstract
The possibility of using micellar electrokinetic chromatography for th e screening of the loop diuretics piretanide and furosemide in urine w as studied. A fast and simple method with good repeatability is descri bed. The method was applied to urine samples collected from a healthy volunteer after oral administration of therapeutic doses of each compo und. Positive identification in the urine matrix was possible through recording diode array spectra.