The present study reviews four cases in which degenerated uterine leio
myomas mimicked appendicitis clinically. The correct diagnosis was mad
e prospectively by sonography in each case. Appendicitis was excluded
by graded compression sonography and an exophytic uterine leiomyoma wa
s identified at the point of maximal symptoms. The leiomyomas demonstr
ated central hypoechoic foci, but no detectable Doppler flow indicatin
g necrosis. Although the phenomenon of a degenerated uterine leiomyoma
mimicking appendicitis clinically is known, sonographic diagnosis has
not been reported previously. The importance of making this diagnosis
sonographically is that management of a degenerated leiomyoma is cons
ervative and unnecessary surgery could be avoided. (C) 1995 John Wiley
& Sons, Inc.