MONOCLONAL GAMMOPATHY IN A DOG WITH CHRONIC PYODERMA

A monoclonal gammopathy composed of immunoglobulin G, with concurrent light-chain proteinuria and generalized lymph node plasmacytosis, was associated with chronic pyoderma in a dog. A uniform population of pla sma cells was observed cytologically and histologically in multiple ly mph node specimens. A diagnosis of monoclonal gammopathy of unknown si gnificance was eventually made by exclusion of other known causes of m onoclonal gammopathy, resolution after antibiotic therapy, and no evid ence of lymphoproliferative disease after 11 months of follow-up and s ubsequent necropsy. This report expands the diagnostic considerations for monoclonal gammopathies in the dog.