ENANTIOSELECTIVE HYDROLYSIS OF 2,2-DISUBSTITUTED OXIRANES MEDIATED BYMICROSOMAL EPOXIDE HYDROLASE

Authors
BASAVAIAH D RAJU SB
Citation
D. Basavaiah et Sb. Raju, ENANTIOSELECTIVE HYDROLYSIS OF 2,2-DISUBSTITUTED OXIRANES MEDIATED BYMICROSOMAL EPOXIDE HYDROLASE, Synthetic communications, 25(21), 1995, pp. 3293-3306
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
25
Issue
21
Year of publication
1995
Pages
3293 - 3306
Database
ISI
SICI code
0039-7911(1995)25:21<3293:EHO2OM>2.0.ZU;2-1
Abstract
2-Aryl-2-methyloxiranes are enantioselectively hydrolyzed with microso mal epoxide hydrolase from pig liver to provide 1,2-diols containing a tertiary benzylic alcohol stereogenic centre upto 34% enantiomeric pu rities.