A. Heisel et al., LOW-ENERGY TRANSVENOUS CARDIOVERSION OF SHORT-DURATION ATRIAL TACHYARRHYTHMIAS IN HUMANS USING A SINGLE-LEAD SYSTEM, PACE, 20(1), 1997, pp. 65-71
HEISEL, A., ET AL.: Low Energy Transvenous Cardioversion of Short Dura
tion Atrial Tachyarrhythmias in Humans Using a Single Lead System, The
purpose of this study was to investigate the efficacy and safety of a
trial cardioversion using an endocardial single lead system presently
used for ventricular defibrillation. The study population consisted of
26 recipients of an ICD in combination with a conventional endocardia
l single lead system with the proximal spring electrode as anode in th
e SVC and the distal as cathode in the apex of the RV. Atrial tachyarr
hythmias were induced by right atrial burst pacing. If the arrhythmia
sustained > 1 minute, biphasic shocks synchronized with the R wave wer
e delivered using the implanted device, beginning with an energy of 4
J. If 4 J failed to terminate the arrhythmia, energy was increased ste
pwise, if the first shock was successful, a step-down testing was perf
ormed after reinduction of atrial tachyarrhythmias. The mean atrial de
fibrillation threshold was 2.3 +/- 1.2 J (range, 0.5-5 J). A total of
154 shocks were delivered and no adverse effects were observed. The me
an defibrillation threshold for atrial flutter was somewhat lower than
that for AF (1.8 +/- 1 J vs 2.7 +/- 1.4 J, P = 0.08). There was no co
rrelation between the atrial defibrillation threshold and a history of
previously occurring atrial tachyarrhythmias, the kind of the underly
ing heart disease, a prescription of antiarrhythmic drugs, the dimensi
on of the LA, the LVEF, or the ventricular DFT. Internal atrial cardio
version of short duration atrial tachyarrhythmias using a transvenous
single lead system designed for ventricular defibrillation is feasible
and safe at low energies, and may have important clinical application
s.