DETECTION OF ALPHA BETA-HYDROLASE FOLD IN THE CELL-SURFACE ESTERASES OF ACINETOBACTER SPECIES USING AN ANALYSIS OF 3D PROFILES/

Authors
ALON RN MIRNY L SUSSMAN JL GUTNICK DL
Citation
Rn. Alon et al., DETECTION OF ALPHA BETA-HYDROLASE FOLD IN THE CELL-SURFACE ESTERASES OF ACINETOBACTER SPECIES USING AN ANALYSIS OF 3D PROFILES/, FEBS letters, 371(3), 1995, pp. 231-235
Citations number
15
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
371
Issue
3
Year of publication
1995
Pages
231 - 235
Database
ISI
SICI code
0014-5793(1995)371:3<231:DOABFI>2.0.ZU;2-V
Abstract
The primary sequence of esterases from Acinetobacter lwoffii RAG-1 and A. calcoaceticus BD413 were compared with linearized structural seque nces of two hundred proteins selected from Brookhaven Protein DataBank using a modified version of the Bowie et al, algorithm [3]. Significa nt structural homology was found to alpha/beta proteins and specifical ly to those with the alpha/beta-hydrolase fold for,which the crystal s tructure was reported. No such homology was detected using common prim ary sequence alignment programs such as FASTA or BLAST.