Rn. Alon et al., DETECTION OF ALPHA BETA-HYDROLASE FOLD IN THE CELL-SURFACE ESTERASES OF ACINETOBACTER SPECIES USING AN ANALYSIS OF 3D PROFILES/, FEBS letters, 371(3), 1995, pp. 231-235
The primary sequence of esterases from Acinetobacter lwoffii RAG-1 and
A. calcoaceticus BD413 were compared with linearized structural seque
nces of two hundred proteins selected from Brookhaven Protein DataBank
using a modified version of the Bowie et al, algorithm [3]. Significa
nt structural homology was found to alpha/beta proteins and specifical
ly to those with the alpha/beta-hydrolase fold for,which the crystal s
tructure was reported. No such homology was detected using common prim
ary sequence alignment programs such as FASTA or BLAST.