The concentration of particles in specialty gas systems can vary not o
nly from point-to-point but also overtime. Such variations are most ev
ident inside a gas cylinder and after pressure reduction. The observed
levels of particulate contamination are not necessarily indicative of
system quality because the measurements depend on the specific point
of sampling and effects such as handling, pressure reduction, chemical
reactions, and settling that lead to particulate variability. New ins
trumentation and measurement strategies are needed to cope with partic
ulate variability in specialty-gas systems.