TISSUE PARAMETERS DETERMINING THE VISUAL APPEARANCE OF NORMAL SKIN AND PORT-WINE STAINS

Citation
Lo. Svaasand et al., TISSUE PARAMETERS DETERMINING THE VISUAL APPEARANCE OF NORMAL SKIN AND PORT-WINE STAINS, Lasers in medical science, 10(1), 1995, pp. 55-65
Citations number
16
Categorie Soggetti
Medical Laboratory Technology
Journal title
ISSN journal
02688921
Volume
10
Issue
1
Year of publication
1995
Pages
55 - 65
Database
ISI
SICI code
0268-8921(1995)10:1<55:TPDTVA>2.0.ZU;2-W
Abstract
Port-wine stain is a congenital birthmark consisting of an abnormal de nsity of blood vessels in the upper dermis. The enlarged blood volume gives the lesion a red to purple colour. The aim of the treatments is to destroy the vessels to the extent necessary for obtaining a normal skin coloration. Thus, in principle, all relevant information about th e lesion should be contained in a reflectance spectrum in the visible. However, the relation between the reflectance spectrum and tissue par ameters such as scattering, melanin content and blood distribution is somewhat composite. This work tries to enlighten this relation in term s of a very simple analytical mathematical model, and it is demonstrat ed that such a model at least will contribute to a qualitative underst anding of the relevance of the various parameters.