LOCALIZATION OF THE GENE FOR HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-2 (HSD11B2)TO CHROMOSOME BAND 16Q22

Authors
KROZOWSKI Z BAKER E OBEYESEKERE V CALLEN DF
Citation
Z. Krozowski et al., LOCALIZATION OF THE GENE FOR HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-2 (HSD11B2)TO CHROMOSOME BAND 16Q22, Cytogenetics and cell genetics, 71(2), 1995, pp. 124-125
Citations number
10
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
71
Issue
2
Year of publication
1995
Pages
124 - 125
Database
ISI
SICI code
0301-0171(1995)71:2<124:LOTGFH>2.0.ZU;2-3
Abstract
The enzyme 11 beta-hydroxysteroid dehydrogenase type 2 (11 beta HSD2) is an NAD-dependent, high-affinity isoform that potently inactivates g lucocorticoids. In the present study we have used fluorescence in situ hybridization and an 11 beta HSD2 cDNA isolated from human kidney as probe to localize the gene encoding 11HSD2. The gene, which has been g iven the symbol HSD11B2, maps to human chromosome band 16q22.