SUCCESSFUL MANAGEMENT WITH INTERFERON ALPHA-2A AFTER PREDNISONE THERAPY FAILURE IN AN INFANT WITH A GIANT CAVERNOUS HEMANGIOMA

Authors
CASTELLO MA RAGNI G ANTIMI A TODINI A PATTI G LUBRANO R CLERICO A CALISTI A
Citation
Ma. Castello et al., SUCCESSFUL MANAGEMENT WITH INTERFERON ALPHA-2A AFTER PREDNISONE THERAPY FAILURE IN AN INFANT WITH A GIANT CAVERNOUS HEMANGIOMA, Medical and pediatric oncology, 28(3), 1997, pp. 213-215
Citations number
20
Categorie Soggetti
Oncology,Pediatrics
Journal title
Medical and pediatric oncology → ACNP
ISSN journal
00981532
Volume
28
Issue
3
Year of publication
1997
Pages
213 - 215
Database
ISI
SICI code
0098-1532(1997)28:3<213:SMWIAA>2.0.ZU;2-6
Abstract
A giant cavernous hemangioma of the left arm with severe thrombocytope nia and consumptive coagulopathy was observed in a neonate. initial tr eatment with prednisone, platelet transfusions, and clotting replaceme nt failed to control the bleedings. The child was then treated with da ily subcutaneous infusions oi interferon alpha-2a. Coagulopathy rapidl y improved and transfusions were drastically reduced. The hemangioma r egressed progressively and disappeared after 4 months of treatment. (C ) 1997 Wiley-Liss, Inc.