IMPAIRMENT OF RENAL-FUNCTION AFTER TREATMENT OF A BURN PATIENT WITH DICLOFENAC, A NONSTEROIDAL ANTIINFLAMMATORY DRUG

Due to pain from infected 12 per cent TBSA flame injuries a 71-year-ol d female was treated with a non-steroidal anti-inflammatory drug (dicl ofenac), thereby inhibiting the synthesis of prostaglandins, and devel oped transient impairment of renal function. This case report indicate s that prostaglandins may be required to modulate the late responses a fter burns or other major trauma, especially when infected.