Objectives: The potential gains in life expectancy of the US populatio
n by the partial and total elimination of deaths from HIV/AIDS were co
mpared with that of deaths from heart disease and malignant neoplasms.
Methods: The data from the 1992 advanced mortality report and detaile
d information provided by the National Center for Health Statistics we
re analysed by using the partial multiple decrement life-table techniq
ue. Results: For the total population of the United States in 1992, th
e gains in future life expectancy through the elimination of deaths fr
om HIV/AIDS, heart disease and malignant neoplasms were 0.34, 3.25 and
3.21 years, respectively. The gains in life expectancy in those of wo
rking age (15-64 years) through the elimination of deaths from these t
hree causes of deaths were 0.20, 0.40 and 0.55 years, respectively. Ra
ce/sex-specific calculations indicate that the total elimination of de
aths from HIV/AIDS, heart disease and malignant neoplasms in white men
of working age resulted in increased life expectancy of 0.28, 0.54 an
d 0.53, respectively, whereas the corresponding figures for black men
were 0.82, 0.90 and 0.76 years, respectively. Although the impact of t
he elimination of the other causes remained relatively stable from 198
7 to 1992, the potential gains in life expectancy for black men of wor
king age by eliminating HIV/AIDS rose from 0.36 years in 1987 to 0.82
years in 1992. For the total US population of working age, the elimina
tion of HIV/AIDS deaths resulted in increased life expectancy similar
to that observed for a 50% reduction of heart disease or malignant neo
plasms, whereas among black men of working age, the increased years of
life expectancy from the elimination of HIV/AIDS deaths were virtuall
y the same as those observed for the elimination of heart disease or m
alignant neoplasms. Conclusions: The potential gains in life expectanc
y by reduction of deaths from heart disease and malignant neoplasms ar
e more heavily influenced by increasing years after the working ages (
15-64 years), whereas the potential gains in life expectancy by reduci
ng deaths from HIV/AIDS make a greater contribution to those of workin
g age. Hence, in terms of the economic costs and benefits, these resul
ts indicate that in evaluating policy issues regarding allocation of r
esearch funds, studies of life expectancy are far more important than
the simple approach which allocates funds on the basis of the number o
f deaths due to Various diseases.