M. Vervoort et al., GENETIC-DETERMINANTS OF SENSE ORGAN IDENTITY IN DROSOPHILA - REGULATORY INTERACTIONS BETWEEN CUT AND POXN, Development, 121(9), 1995, pp. 3111-3120
Two genes involved in defining the type of sense organ have been ident
ified in Drosophila. The gene cut differentiates the external sense or
gans (where it is expressed) from the chordotonal organs (where it is
not); among the external sense organs poxn differentiates the poly-inn
ervated organs (where it is expressed) from the mono-innervated organs
(where it is not), Here we show that the expression of poxn in normal
embryos does not depend on cut, and that poxn is capable of inducing
the expression of cut. We have identified a small domain of the very l
arge cut regulatory region as a likely target for activation by poxn.