REMISSION OF SEVERE EPIDERMOLYSIS-BULLOSA ACQUISITA INDUCED BY EXTRACORPOREAL PHOTOCHEMOTHERAPY

Authors
MILLER JL STRICKLIN GP FINE JD KING LE ARZUBIAGA MD ELLIS DL
Citation
Jl. Miller et al., REMISSION OF SEVERE EPIDERMOLYSIS-BULLOSA ACQUISITA INDUCED BY EXTRACORPOREAL PHOTOCHEMOTHERAPY, British journal of dermatology, 133(3), 1995, pp. 467-471
Citations number
22
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
British journal of dermatology → ACNP
ISSN journal
00070963
Volume
133
Issue
3
Year of publication
1995
Pages
467 - 471
Database
ISI
SICI code
0007-0963(1995)133:3<467:ROSEAI>2.0.ZU;2-T
Abstract
We report a patient with severe epidermolysis bullosa acquisita (EBA) whose disease was refractory to conventional treatments. New bullae co ntinued to develop over greater than 50% of his body surface area desp ite therapy. His course was complicated by hyperglycaemia, sepsis, hyp oxia caused by pulmonary Aspergillus infection and an idiopathic cardi omyopathy. His EBA resolved after treatment with extracorporeal photoc hemotherapy (ECP). Hence, ECP may be effective in the treatment of sev ere EBA which has failed to respond to standard treatment regimens.