A NEW ROUTE TO N-SUBSTITUTED 11-AZAARTEMISININS

Authors
MEKONNEN B ZIFFER H
Citation
B. Mekonnen et H. Ziffer, A NEW ROUTE TO N-SUBSTITUTED 11-AZAARTEMISININS, Tetrahedron letters, 38(5), 1997, pp. 731-734
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
5
Year of publication
1997
Pages
731 - 734
Database
ISI
SICI code
0040-4039(1997)38:5<731:ANRTN1>2.0.ZU;2-B
Abstract
A series of N-substituted 11-azaartemisinins were prepared in high yie ld by Michael additions to the amide nitrogen in 2a. The presence of s ubstituents on the unsaturated system of the Michael acceptor markedly decreased the yield of the reaction. (C) 1997, Elsevier Science Ltd.