A SIMPLE, CONVENIENT, GENERAL PROCEDURE FOR THE SYNTHESIS OF 2-ALKYN-1-YLBORONATES

Representative 2-alkyn-1-ylboronates have been synthesized in good to excellent yields using the reaction of the newly available diisopropyl iodomethylboronate with alkynyllithiums generated in situ. Comparable yields are obtained from both acyclic and cyclic boronates. However, odomethyl)-1,3,2-dioxa-4,4,5,5-tetramethylborolane gave superior yield s with a wide variety of alkynyllithiums. This procedure offers a simp le and convenient alternative route to existing methodologies in terms of the milder reaction condition and the ease of the operation. (C) 1 997, Elsevier Science Ltd.