B,B-DIHALOALKYLBORANES AS EFFICIENT REAGENTS FOR THE STEREOSELECTIVE SYNTHESIS OF SYN-ALDOLS

Authors
RAMACHANDRAN PV XU WC BROWN HC
Citation
Pv. Ramachandran et al., B,B-DIHALOALKYLBORANES AS EFFICIENT REAGENTS FOR THE STEREOSELECTIVE SYNTHESIS OF SYN-ALDOLS, Tetrahedron letters, 38(5), 1997, pp. 769-772
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
5
Year of publication
1997
Pages
769 - 772
Database
ISI
SICI code
0040-4039(1997)38:5<769:BAERFT>2.0.ZU;2-C
Abstract
The easily synthesized B,B-dihaloalkylboranes, in the presence of eith er Et(3)N or i-Pr(2)NEt, converts ethyl ketones, RCOEt, to 96-greater than or equal to 99% Z-enolates, converted by aldehydes to essentially pure syn-aldols. (C) 1997, Elsevier Science Ltd.