Concerns about the frequency and consequences of adverse drug reaction
s have prompted the Department of Veterans' Affairs to establish a 'qu
ality use of medicines' program. This involves several approaches, inc
luding patient and pharmacist education and prescriber pharmaceutical
feedback, The traditional approach, regulatory change, is also used to
influence prescribing The process of prescribing feedback involves th
e identification of high risk prescribing situations, such as the pres
cribing of drug combinations known to interact significantly. Analysis
of prescribing information for veterans indicates the extent to which
these 'high risk' situations occur. Increased regulation for tire pre
scribing of certain of the benzodiazepines on the Repatriation Pharmac
eutical Benefits Scheme was introduced in April 1993. Analysis of drug
utilisation, using the Department of Veterans' Affairs pharmaceutical
database reveals, not surprisingly, that this has had a dramatic effe
ct on the prescribing of the newly restricted drugs, Tire prescribing
of all benzodiazepines including restricted and unrestricted drugs how
ever, has dropped by a net of 11% when comparing twelve month periods
before and after the introduction of restrictions, Equally importantly
, the prescribing of tricyclic antidepressants (TCA) has not significa
ntly changed implying that prescribers are not routinely changing from
benzodiazepines to TCAs.