NORMAL-PREGNANCY IN PRIMARY ALVEOLAR HYPOVENTILATION TREATED WITH NOCTURNAL NASAL INTERMITTENT POSITIVE PRESSURE VENTILATION

Citation
T. Pieters et al., NORMAL-PREGNANCY IN PRIMARY ALVEOLAR HYPOVENTILATION TREATED WITH NOCTURNAL NASAL INTERMITTENT POSITIVE PRESSURE VENTILATION, The European respiratory journal, 8(8), 1995, pp. 1424-1427
Citations number
18
Categorie Soggetti
Respiratory System
ISSN journal
09031936
Volume
8
Issue
8
Year of publication
1995
Pages
1424 - 1427
Database
ISI
SICI code
0903-1936(1995)8:8<1424:NIPAHT>2.0.ZU;2-F
Abstract
Nocturnal nasal intermittent positive pressure ventilation (NIPPV) is increasingly used to treat chronic respiratory failure in a wide varie ty of conditions (myopathies, Ondine's curse, kyphoscoliosis, etc.) an d allows a normal everyday life. Some of these diseases affect women o f childbearing age. We report on a young woman suffering from primary alveolar hypoventilation, who presented with limitation of daytime act ivities, severe oxygen desaturation during sleep, polycythaemia and pu lmonary hypertension. These abnormalities completely reversed after a few months of NIPPV applied through a nasal mask. Whilst under ventila tory assistance during sleep, she had an uneventful pregnancy and deli very of a normal baby. We suggest that in selected patients requiring NIPPV, pregnancy can be contemplated with a reasonable level of safety both for the mother and the child, provided that adequate mechanical ventilatory assistance during sleep is maintained throughout pregnancy .