Mh. Vuento et al., EVALUATION OF OVARIAN FINDINGS IN ASYMPTOMATIC POSTMENOPAUSAL WOMEN WITH COLOR DOPPLER ULTRASOUND, Cancer, 76(7), 1995, pp. 1214-1218
Background. To evaluate the prevalence and significance of abnormal ov
arian findings in asymptomatic postmenopausal women, screening for ova
rian cancer with color Doppler ultrasound was performed. Methods. One
thousand three hundred sixty-four asymptomatic women aged 56-61 years
(mean, 59 years) were examined by color Doppler sonography. Ninety-six
percent of the examinations were transvaginal and 4% transabdominal.
The criteria for abnormality were an ovarian volume 8 cm(3) or greater
, nonuniform echogenicity, and/or pulsatility index (PI) of the ovaria
n artery or tumor vessel, if present, 1.0 or less. Repeat sonograms we
re performed 1-3 months later on all patients with abnormal findings,
and exploratory laparotomy was performed if a malignant tumor was susp
ected. Results. Abnormal ovarian findings were detected in 160 women (
12%). At the time of repeat sonogram there were 28 persisting abnormal
ities (2%). At that time, the ovary was regarded as normal if it still
contained a small clear cyst with an unchanged greatest dimension of
less than 20 mm. Three women had a low PI value but all had also abnor
mal ovarian sonographic morphology. Two ultrasound-guided cyst punctur
es were performed and three patients had surgery; one benign serous cy
st, one benign serous cystadenoma, and one serous cystadenoma of borde
rline malignancy were detected. The remaining abnormal findings disapp
eared or remained unchanged during a minimum follow-up of 2 years. One
case of Stage IA ovarian cancer has been reported 2 years after a neg
ative screening and one abdominal carcinomatosis 2 1/2 years after a n
egative screening result.Conclusions. There is a high frequency of sma
ll ovarian cysts in asymptomatic postmenopausal women. A large percent
age of these cysts regress spontaneously or remain unchanged. Transvag
inal color Doppler ultrasound is an effective method for detecting the
se lesions. Color Doppler does not increase substantially the number o
f operations for benign reasons. However, as a primary screening modal
ity, the conventional sonography seems to be quite sufficient.