GROWTH-HORMONE DEFICIENCY AND EMPTY SELLA IN DIDMOAD SYNDROME - AN ENDOCRINE STUDY

Authors
SOLIMAN AT BAPPAL B DARWISH A RAJAB A ASFOUR M
Citation
At. Soliman et al., GROWTH-HORMONE DEFICIENCY AND EMPTY SELLA IN DIDMOAD SYNDROME - AN ENDOCRINE STUDY, Archives of Disease in Childhood, 73(3), 1995, pp. 251-253
Citations number
6
Categorie Soggetti
Pediatrics
Journal title
Archives of Disease in Childhood → ACNP
ISSN journal
00039888
Volume
73
Issue
3
Year of publication
1995
Pages
251 - 253
Database
ISI
SICI code
0003-9888(1995)73:3<251:GDAESI>2.0.ZU;2-#
Abstract
Two girls with DIDMOAD syndrome are presented. One also had severe meg aloblastic-sideroblastic anaemia and the other several neurological ma nifestations. Both were short with defective growth hormone secretion. Computed tomography revealed empty sella in both girls; one had wides pread atrophic cortical and cerebellar changes. High doses of thiamine improved the anaemia in the first case increased C peptide secretion in both, but had no effect on the neurological abnormalities.