ADDITIONAL PROOF OF REDUCTION OF ETHANOL ABSORPTION FROM RAT INTESTINE IN-VIVO BY HIGH ACETALDEHYDE CONCENTRATIONS

Authors
KINOSHITA H IJIRI I AMENO S FUKE C AMENO K
Citation
H. Kinoshita et al., ADDITIONAL PROOF OF REDUCTION OF ETHANOL ABSORPTION FROM RAT INTESTINE IN-VIVO BY HIGH ACETALDEHYDE CONCENTRATIONS, Alcohol and alcoholism, 30(4), 1995, pp. 419-421
Citations number
15
Categorie Soggetti
Substance Abuse
Journal title
Alcohol and alcoholism → ACNP
ISSN journal
07350414
Volume
30
Issue
4
Year of publication
1995
Pages
419 - 421
Database
ISI
SICI code
0735-0414(1995)30:4<419:APOROE>2.0.ZU;2-B
Abstract
We investigated intestinal ethanol absorption in rats pretreated with saline, cyanamide, 4-methylpyrazole and cyanamide + 4-methylpyrazole. The value of the absorption rate constant in the cyanamide-pretreated group with high acetaldehyde levels was the lowest among the four grou ps, but there were no significant differences among the remaining grou ps. We found that high acetaldehyde concentration itself clearly reduc es intestinal ethanol absorption.