Em. Ferdeghini et al., ASSESSMENT OF NORMAL TESTIS GROWTH BY QUANTITATIVE TEXTURE ANALYSIS OF 2-D ECHO IMAGES, Medical engineering & physics, 17(7), 1995, pp. 523-528
Size phases summarize the evolution of the healthy male gonad. Qualita
tive examination of two-dimensional echograms detects tonal difference
s at different ages of the testes. However, routine qualitative evalua
tion of the echograms is too subjective and dependent upon the scanner
controls; on the other hand, simple morphology reports are not suffic
ient to establish the correct histolologic and physiologic evolution.
So far computer-assisted quantitative analysis of ultrasonic images ha
s been successful in the characterization of tissues based on their ec
hographic properties; thus this approach could be suitable for art acc
urate identification of the age of healthy testis. Sixty-two normal su
bjects, ranked in six groups according to age, underwent echographic e
xamination in standard conditions. Echograms were digitized and analys
ed by means of well-established algorithms for first and second order
statistics. Significant differences in tonal features were found able
to discriminate among different ages, in agreement with the qualitativ
e analysis and the histologic reports. Furthermore, same second order
analysis features exhibit statistically significant alterations of the
micro-structural organisation of the echo patients consequent to chan
ges of the configuration of the ultrasonic targets, that is, of the go
nad's histology. In conclusion quantitative analysis of echograms can
provide a tool for a better assessment of normal testis evolution than
the qualitative approach.