HTLV-II INFECTION IN SPAIN - ANALYSIS OF 113 CASES IDENTIFIED UP TO NOVEMBER 1994

BACKGROUND: HTLV-II is a human retrovirus considered to be responsible for the genesis of some lymphoproliferative and neurologic syndromes. The virus is endemic in some Amerindian and African tribes as well as amongts injecting drug addicts (IDA) in North America and Europe. MET HODS: The clinical, epidemiologic and virologic characteristics of the patients with HTLV-II infection identified in Spain up to November 19 94 are described. RESULTS: One hundred thirteen subjects have been ide ntified with HTLV-II infection in Spain with 4 being African immigrant s residing in Madrid and the remaining being IDA from other European c ountries. Most were males (94/113; 83%). Art were IDA except six (5 ha d acquired the infection by sexual contact and one by blood transfusio n). Most of the IDA infected with HTLV-II were coinfected with HIV-I ( 93/113; 83%). No patient showed clinical manifestations attributable t o HTLV-II infection although one drug addict male coinfected with HIV- 1 and HTLV-II developed a non-inflammatory proximal myopathy. CONCLUSI ONS: Infection by HTLV-II is present in Spain and affects with prefere nce to injecting drug addicts, It has been shown to be of growing inci dence with a current global prevalence of 2% in IDA.