CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION STUDIES OF COMPLEXES BETWEEN AN INFLUENZA HEMAGGLUTININ AND FAB FRAGMENTS OF 2 DIFFERENT MONOCLONAL-ANTIBODIES

Authors
GIGANT B FLEURY D BIZEBARD T SKEHEL JJ KNOSSOW M
Citation
B. Gigant et al., CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION STUDIES OF COMPLEXES BETWEEN AN INFLUENZA HEMAGGLUTININ AND FAB FRAGMENTS OF 2 DIFFERENT MONOCLONAL-ANTIBODIES, Proteins, 23(1), 1995, pp. 115-117
Citations number
12
Categorie Soggetti
Biology
Journal title
Proteins → ACNP
ISSN journal
08873585
Volume
23
Issue
1
Year of publication
1995
Pages
115 - 117
Database
ISI
SICI code
0887-3585(1995)23:1<115:CAPDSO>2.0.ZU;2-P
Abstract
Fab fragments from two different monoclonal antibodies (BH151 and HC45 ) which bind to the same antigenic region of the influenza hemagglutin in were crystallized as complexes with the hemagglutinin. The complexe s crystallize in PEG 600, pH 6.0, and PEG 2000, pH 8.5, respectively. Both crystals belong to space group P321, with very similar unit cell dimensions. (C) 1995 Wiley-Liss, Inc.