Results are reported on observations obtained with the Oriented Scinti
llation Spectrometer Experiment (OSSE) instrument on the Compton Gamma
Ray Observatory (CGRO) of 17 active galactic nuclei (AGNs) known to e
xhibit blazar properties at other wavelengths. These observations span
the period from 1991 June through 1994 May. Of the 33 high-confidence
EGRET detections of blazars during CGRO observing phases 1 and 2 (199
1 May 16-1993 September 7), OSSE has observed eight and detected five,
namely 3C 273, 3C 279, PKS 0528+134, CTA 102, and 3C 454.3. Additiona
lly, OSSE has detected the BL Lac sources H1517+65.6 and PKS 2155-304,
which were not detected with EGRET. Variability in the energy band 50
-150 keV is observed for all of the detected AGNs. The OSSE blazar sou
rces are all well described by simple power-law models with photon num
ber indices, Gamma, varying from 1.0 to 2.1 among sources. When combin
ed with available, although not necessarily contemporaneous, COMPTEL a
nd EGRET observations, four to five detected blazars show clear eviden
ce for spectral breaks between the hard X-ray and medium-energy gamma-
ray bands. The exception is the combined OSSE/EGRET data for 3C 279 du
ring 1991 October, where a simple power law with Gamma approximate to
1.9 works equally well. Gamma-ray evidence for beaming in CTA 102, PKS
0528+134, and 3C 454.3 is presented.