SPINDLE-CELL HEMANGIOENDOTHELIOMA OF THE ORAL CAVITY - A CASE-REPORT

We describe a vascular tumor classified as SCH by histological criteri a that was found in the mandibular-buccal fold of a 12-year-old girl. Microscopically, the lesion consisted of thin-walled cavernous spaces containing thrombi and phleboliths, and cellular areas composed of spi ndle-shaped, epithelioid and vacuolated cells. Immunohistochemically, the endothelial vascular lining was highly reactive with HAM56 antibod y, while variable reactivity was observed for factor VIII-associated a ntigen. All cell types were positive for vimentin and anti-PCNA staine d less than 3% of the tumor cells, This is the first report of SCH in the oral cavity.