EFFECTS OF ACYL-GROUPS AND ETHANOL RATIOS ON LIPASE-CATALYZED REGIOSELECTIVE DEACYLATION IN PERACYLATED METHYL GLYCOPYRANOSIDES

Authors
HSIAO KF YANG FL WU SH WANG KT
Citation
Kf. Hsiao et al., EFFECTS OF ACYL-GROUPS AND ETHANOL RATIOS ON LIPASE-CATALYZED REGIOSELECTIVE DEACYLATION IN PERACYLATED METHYL GLYCOPYRANOSIDES, Biotechnology letters, 17(9), 1995, pp. 963-968
Citations number
26
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
17
Issue
9
Year of publication
1995
Pages
963 - 968
Database
ISI
SICI code
0141-5492(1995)17:9<963:EOAAER>2.0.ZU;2-I
Abstract
Regioselective ethanolysis of peracylated methyl beta, alpha-D-glucopy ranoside and methyl alpha-D-mannopyranoside in anhydrous organic solve nt (n-hexane/EtOH = 99/1) could afford 6-OH derivatives exclusively by Candida rugosa lipase (CPL). No 4 --> 6 acyl migration was observed i n such an anhydrous solvent system. Substrates with propanoyl groups w ere more reactive than with acetyl groups on CRL-catalyzed reactions.