EXTRACELLULAR LIGNIN AND MANGANESE PEROXIDASE PRODUCTION BY THE WHITE-ROT FUNGUS CORIOLUS-VERSICOLOR-290

Lignin peroxidase (LiP) and manganese peroxidase (MnP) activity in Cor iolus versicolor 290 reach maximal levels after 8 and 10 days growth r espectively. Increases in LIP activity were observed upon supplementat ion of the medium with veratryl alcohol. The physiology of this strain is quite distinct from that of the better studied Phanerochaete chrys osporium in that extracellular LIP activity is enhanced at carbon leve ls of 10g/L(-1), This increase in LIP enzyme activity at higher carbon levels appears to be mediated at the transcriptional level, given tha t lip and mnp mRNA levels mirror the observed enzyme activity levels q uite closely.