IN-VITRO EVALUATION OF THE CYTOTOXICITY OF CALCIUM HYDROXIDE-BASED ROOT-CANAL SEALERS

Authors
BELTES P KOULAOUZIDOU E KOTOULA V KORTSARIS AH
Citation
P. Beltes et al., IN-VITRO EVALUATION OF THE CYTOTOXICITY OF CALCIUM HYDROXIDE-BASED ROOT-CANAL SEALERS, Endodontics & dental traumatology, 11(5), 1995, pp. 245-249
Citations number
NO
Categorie Soggetti
Dentistry,Oral Surgery & Medicine
Journal title
Endodontics & dental traumatology → ACNP
ISSN journal
01092502
Volume
11
Issue
5
Year of publication
1995
Pages
245 - 249
Database
ISI
SICI code
0109-2502(1995)11:5<245:IEOTCO>2.0.ZU;2-K
Abstract
The cytotoxicity of three calcium hydroxide-containing root canal seal ers (Sealapex, CRCS and Apexit) was tested by using L929 and BHK 21/C1 3 cells. After setting for 24h, the sealers were covered with cell sus pension. Cytotoxicity was determined by a quantitative technique at 24 h, 48h and 72h. All the sealers were found to be cytotoxic. Sealapex s howed the highest cytotoxicity, causing a significant decrease in cell density. CRCS was less toxic than Sealapex and more toxic than Apexit . Apexit proved to be the least toxic material.