The minimum population size required for selection in order to reduce
the effect of genetic drift to a particular level has been considered.
The model of Nicholas was extended to include the measurement-error v
ariance in the response variance. Situations where the sex ratios amon
g scored and breeding individuals are unequal are also considered. Whe
n the duration of a selection experiment is relatively long, Nicholas'
approximation (i.e., assuming that measurement error is negligible re
lative to drift) is useful in determining the minimum effective popula
tion size required. However, the measurement-error variance becomes an
important source of variation in short-term (less than or equal to 5
generations) selection experiments, and should not be ignored.