Sequestration, the adherence of infected erythrocytes containing the m
ore mature stages of parasite development (trophozoites and schizonts)
to the endothelial cells lining the capillaries and post-capillary ve
nules, is characteristic of Plasmodium falciparum infections. In this
review, Irwin Sherman and his colleagues discuss recent advances in th
e characterization of the adhesive molecules on the surface of malaria
-infected erythocytes and the receptors on the endothelium to which th
ey bind.