CHEMISTRY OF VERONGIDA SPONGES .5. BROMINATED METABOLITES FROM THE CARIBBEAN SPONGE PSEUDOCERATINA SP

A detailed analysis of the chemical constituents of a Caribbean specim en of Pseudoceratina sp. which, on the basis of its morphological char acters, seems to be different from the hitherto described three Pseudo ceratina species, was performed. This study led to the isolation of ni ne brominated products (1-9), one of which is a new bromotyrosine meta bolite. The proposed structure of the new compound 1 is based on spect ral arguments. Compounds 1 and 2, which are the major brominated metab olites of our specimen and which have not yet been isolated from any P seudoceratina species, could be usefully employed as chemotaxonomic ma rkers.