RELAXIN LEVELS IN AMNIOTIC-FLUID, EXTRAEMBRYONIC CELOMIC FLUID AND MATERNAL SERUM IN EARLY HUMAN-PREGNANCY

Citation
Nc. Wathen et al., RELAXIN LEVELS IN AMNIOTIC-FLUID, EXTRAEMBRYONIC CELOMIC FLUID AND MATERNAL SERUM IN EARLY HUMAN-PREGNANCY, Early human development, 43(1), 1995, pp. 71-74
Citations number
9
Categorie Soggetti
Obsetric & Gynecology",Pediatrics
Journal title
ISSN journal
03783782
Volume
43
Issue
1
Year of publication
1995
Pages
71 - 74
Database
ISI
SICI code
0378-3782(1995)43:1<71:RLIAEC>2.0.ZU;2-J
Abstract
Separately identified samples of amniotic fluid and extraembryonic coe lomic fluid together with maternal serum were collected from 22 women between 8 and 11 weeks of pregnancy and analysed for relaxin by immuno assay. Relaxin levels in maternal serum (median 1085 pg/ml; range 390- 1259 pg/ml) were substantially higher than those in extraembryonic coe lomic fluid (median 57.5 pg/ml; range 17-145 pg/ml; P < 0.0001; Mann-W hitney U-test). In turn, the levels of relaxin in coelomic fluid were higher than those in amniotic fluid (median 10 pg/ml; range 10-37 pg/m l; P < 0.0001; Mann-Whitney U-test). A linear correlation was found be tween relaxin levels in maternal serum and coelomic fluid (r = 0.68; P = 0.001) but there was no relation between levels in the other fluid compartments.