SEQUENCE OF THE PROMOTER REGION OF THE MOUSE GENE ENCODING ORNITHINE AMINOTRANSFERASE

Authors
SHULL JD ESUMI N COLWELL AS PENNINGTON KL JENDOUBI M
Citation
Jd. Shull et al., SEQUENCE OF THE PROMOTER REGION OF THE MOUSE GENE ENCODING ORNITHINE AMINOTRANSFERASE, Gene, 162(2), 1995, pp. 275-277
Citations number
21
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
162
Issue
2
Year of publication
1995
Pages
275 - 277
Database
ISI
SICI code
0378-1119(1995)162:2<275:SOTPRO>2.0.ZU;2-C
Abstract
We have isolated and sequenced the promoter region of the mouse gene ( mOAT) encoding ornithine aminotransferase. A comparison of these mOAT sequences with previously reported sequences for the rat and human gen es encoding .OAT, rOAT and hOAT, respectively, revealed a 256-bp regio n flanking the transcription start point that is highly conserved betw een the three genes. This region contains sequence motifs resembling b inding sites for general transcription factors, as well as other trait s-acting regulatory proteins.