MOLECULAR CHARACTERIZATION OF FRPB, THE 70-KILODALTON IRON-REGULATED OUTER-MEMBRANE PROTEIN OF NEISSERIA-MENINGITIDIS

Authors
PETTERSSON A MAAS A VANWASSENAAR D VANDERLEY P TOMMASSEN J
Citation
A. Pettersson et al., MOLECULAR CHARACTERIZATION OF FRPB, THE 70-KILODALTON IRON-REGULATED OUTER-MEMBRANE PROTEIN OF NEISSERIA-MENINGITIDIS, Infection and immunity, 63(10), 1995, pp. 4181-4184
Citations number
36
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
63
Issue
10
Year of publication
1995
Pages
4181 - 4184
Database
ISI
SICI code
0019-9567(1995)63:10<4181:MCOFT7>2.0.ZU;2-M
Abstract
The structural gene encoding the 70-kDa outer membrane protein FrpB of Neisseria meningitidis was cloned and sequenced. A mutant lacking Frp B was constructed. No difference in iron utilization between the mutan t and the parental strain was observed. A minor effect of the mutation on serum resistance was observed. A topology model for FrpB in the ou ter membrane is proposed.