ADENOVIRUS SEROTYPE-1 DOES NOT ACT SYNERGISTICALLY WITH MORAXELLA (BRANHAMELLA) CATARRHALIS TO INDUCE OTITIS-MEDIA IN THE CHINCHILLA

Authors
BAKALETZ LO MURWIN DM BILLY JM
Citation
Lo. Bakaletz et al., ADENOVIRUS SEROTYPE-1 DOES NOT ACT SYNERGISTICALLY WITH MORAXELLA (BRANHAMELLA) CATARRHALIS TO INDUCE OTITIS-MEDIA IN THE CHINCHILLA, Infection and immunity, 63(10), 1995, pp. 4188-4190
Citations number
33
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
63
Issue
10
Year of publication
1995
Pages
4188 - 4190
Database
ISI
SICI code
0019-9567(1995)63:10<4188:ASDNAS>2.0.ZU;2-X
Abstract
A chinchilla model of otitis media in which adenovirus compromise of t he tubotympanum facilitates the subsequent induction of middle ear dis ease was used to investigate Moraxella (Branhamella) catarrhalis patho genesis. Intranasally inoculated M. catarrhalis did readily colonize t he nasopharynx of this host; however, despite evidence of viral infect ion and tubotympanal compromise, M. catarrhalis did not induce culture -positive otitis media in this model.