We present a model-independent study of spectator effects, which are r
esponsible for the lifetime differences between beauty hadrons. These
effects can be parametrized in terms of hadronic matrix elements of fo
ur four-quark operators. For B mesons, the coefficients of the non-fac
torizable operators rum out to be much larger than those of the factor
izable ones, limiting considerably the usefulness of the vacuum insert
ion approximation. Non-factorizable contributions to the lifetime rati
o tau(B-)/tau(B-d) could naturally be of order 10-20%, and not even th
e sign of these contributions can be predicted at present. In the case
of the Lambda(b) baryon, heavy-quark symmetry is used to reduce the n
umber of independent matrix elements from four to two. In order to exp
lain the large deviation from unity in the experimental result for tau
(Lambda(b))/tau(B-d), it is necessary that these baryon matrix element
s be much larger than those estimated in quark models. We have also re
examined the theoretical predictions for the semileptonic branching ra
tio of B mesons and charm counting, finding that, given the present th
eoretical and experimental uncertainties, there is no significant disc
repancy with experiment.