HINF-I TSP509-I AND BSOF-I POLYMORPHISMS IN THE FLANKING REGIONS OF THE HUMAN VNTR LOCUS D1S80/

Authors
DUNCAN GT BALAMURUGAN K BUDOWLE B TRACEY ML
Citation
Gt. Duncan et al., HINF-I TSP509-I AND BSOF-I POLYMORPHISMS IN THE FLANKING REGIONS OF THE HUMAN VNTR LOCUS D1S80/, GENET A-BIO, 13(5), 1996, pp. 119-121
Citations number
9
Categorie Soggetti
Genetics & Heredity","Biochemical Research Methods
Journal title
GENETIC ANALYSIS-BIOMOLECULAR ENGINEERING → ACNP
ISSN journal
10503862
Volume
13
Issue
5
Year of publication
1996
Pages
119 - 121
Database
ISI
SICI code
1050-3862(1996)13:5<119:HTABPI>2.0.ZU;2-D
Abstract
The minisatellite locus D1S80 (1p35-p36), is a highly polymorphic VNTR that also contains a Hinf I polymorphism in the 5' flanking region. O ur data suggests that the Hinf I polymorphism is a G > T transversion 58 bases downstream from the forward primer. This G > T transversion a lso creates a Tsp509 I restriction sire. Additionally, a G > C transve rsion polymorphism was identified in the 3' flanking region by the cre ation of a BsoF I restriction sire immediately adjacent to the repeat region. Copyright (C) 1996 Elsevier Science B.V.