SCREENING OF MELANIN BIOSYNTHESIS INHIBITORS FROM MARINE MICROALGAE USING STREPTOMYCES-BIKINIENSIS BIOASSAY

Authors
WACHI Y SODE K HORIKOSHI K TAKEYAMA H MATSUNAGA T
Citation
Y. Wachi et al., SCREENING OF MELANIN BIOSYNTHESIS INHIBITORS FROM MARINE MICROALGAE USING STREPTOMYCES-BIKINIENSIS BIOASSAY, Biotechnology techniques, 9(9), 1995, pp. 633-636
Citations number
7
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology techniques → ACNP
ISSN journal
0951208X
Volume
9
Issue
9
Year of publication
1995
Pages
633 - 636
Database
ISI
SICI code
0951-208X(1995)9:9<633:SOMBIF>2.0.ZU;2-5
Abstract
Inhibitors of melanin biosynthesis from marine microalgae were screene d against a melanin-producing microorganism, Streptomyces bikiniensis. From 28 marine microalgal strains, 5 were found showing inhibitory ac tivity. Of these, the extracts (50 mu l, 2 mu g total organic carbon/m u l) from two marine green algae showed strongly inhibited melanin bio synthesis, but showed less than 30 % inhibitory activity against mushr oom tyrosinase.