DERACEMIZATION PROCESS OF ALPHA-AMINOESTE RS VIA PYRIDOXAL .1. SYNTHESIS AND ACTIVITY OF POLYMERIZABLE FORMS OF PYRIDOXAL

Deracemization process of alpha-aminoesters via pyridoxal. I. - Synthe sis and activity of polymerizable forms of pyridoxal. In order to immo bilize pyridoxal, which is a racemization agent of alpha-aminoesters a nd could be used in an cr-aminoacid deracemization process, two polyme rizable analogues of this coenzyme have been synthesized. They were ob tained by functionalization in the 2' or 5' position of the pyridinic ring, by a chain containing an acryloyl end group. Their catalytic act ivity in the homogeneous phase were evaluated in biomimetic conditions (water, pH 7, 25 degrees C), was the same as in the case of pyridoxal .