DERACEMIZATION OF ALPHA-AMINOESTERS VIA P YRIDOXAL .2. STUDY OF COPOLYMERIZATION OF POLYMERIZABLE FORMS OF PYRIDOXAL - REACTIVITY OF CORRESPONDING POLYMERS

Deracemization of alpha-aminoesters via pyridoxal. II [1]. - Study of copolymerization of polymerizable forms of pyridoxal. Reactivity of co rresponding polymers. We studied the copolymerization of pyridoxal (PL ) polymerizable forms, in the presence of two different comonomers (a diluting and crosslinking agent) and the catalytic activity of the cor responding polymers on the alpha-aminoester racemization. We discuss t he choice of these comonomers in the polymerization and also their con centration. Thus, using 4-acryloylmorpholine as a diluting agent, we o btained a sufficiently hydrophilic polymer in an aqueous medium, and t he partition coefficient of the substrate was more favorable. In addit ion, polymer IV, in which the arm allowing immobilization of PL is mos t distant from the catalytic site, had the highest activity.