SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF LANTHANIDE(III) COMPLEXES WITH A HYDRAZONE DERIVED FROM A NEW AMIDO ACID AND THIOSEMICARBAZIDE

Twelve lanthanide (III) complexes, with the general formula Ln(PAAT)(3 ) 5H(2)O (where Ln=La - Yb, except Pm and Tm; HPAAT = yl)propionyl]ami noacetophenone-thiosemicarbazone), have been synthesized and character ized on the basis of elemental analyses, IR, H-1 NMR spectra, molar co nductance measurements, magnetic moments and TG-DTA methods. The analy tical data suggest eight-coordination around the Ln(3+) ion with two c oordinated water molecules. Preliminary pharmacological tests on these complexes showed some antibacterial activity.