L. Ping et al., ACTIVE CONSTITUENTS OF THE BULBS OF FRITILLARIA-EBEIENSIS AND THEIR ANTITUMOR-ACTIVITY IN MICE, PTR. Phytotherapy research, 9(6), 1995, pp. 460-462
The crude alkaloid of Fritillaria ebeiensis G. D. Yu et G. Q. Ji, admi
nistrated orally at a given dose, showed strong antitumour activity in
inhibiting the growth of the solid type of hepatoma in mice. Chemical
studies revealed that the active principles in this crude drug were v
erticine, verticinone and ebeiedine obtained from this species for the
first time. This paper deals with the isolation and activity of these
principles.