Rationale and Objectives. We constructed a near-anatomically correct l
arge-vessel phantom to perform repeatable flow dynamics research exami
nations by angiography, magnetic resonance (MR) angiography, and compu
ted tomography (CT) angiography. Methods. An internal carotid artery w
as constructed within a head phantom. The internal carotid artery bran
ches into a middle and an anterior cerebral artery; the former trifurc
ates and ends in the superior sagittal sinus, and the latter ends in t
he inferior sagittal sinus. A transverse and sigmoid sinus drains the
model. All four vessels connecting the arterial and venous vessels hav
e variable flow-constricting ligatures placed around them. These ligat
ures are accessible on the skull surface. The skull cavity is filled w
ith a silicone polymer that is isodense to brain on CT scans and isoin
tense on most MR images. Results. The flow in the phantom's vessels ma
y be varied in a repeatable manner. Multiple scan sequences may be per
formed without the image degradation caused by patient motion. The hom
ogeneity of the filler polymer allows visualization of flow-related ar
tifacts that may be hidden by complex human anatomy. Conclusion. Preli
minary images of each modality show promise for use of the phantom in
imaging research on large-vessel flow dynamics.