2 AMINO-ACID AMIDOHYDROLASE GENES ENCODING L-STEREOSPECIFIC CARBAMOYLASE AND AMINOACYLASE ARE ORGANIZED IN A COMMON OPERON IN BACILLUS-STEAROTHERMOPHILUS

Authors
BATISSE N WEIGEL P LECOCQ M SAKANYAN V
Citation
N. Batisse et al., 2 AMINO-ACID AMIDOHYDROLASE GENES ENCODING L-STEREOSPECIFIC CARBAMOYLASE AND AMINOACYLASE ARE ORGANIZED IN A COMMON OPERON IN BACILLUS-STEAROTHERMOPHILUS, Applied and environmental microbiology, 63(2), 1997, pp. 763-766
Citations number
16
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Applied and environmental microbiology → ACNP
ISSN journal
00992240
Volume
63
Issue
2
Year of publication
1997
Pages
763 - 766
Database
ISI
SICI code
0099-2240(1997)63:2<763:2AAGEL>2.0.ZU;2-T
Abstract
The L-carbamoylase gene (amaB) upstream of the previously detected L-a minoacylase gene (amaA) in the Bacillus stearothermophilus NCIB8224 st rain was identified in this study. The amaB and amaA genes are cotrans cribed as a single mRNA from the same transcriptional start. The two-a ma-gene operon is conserved in B. stearothermophilus strains. A cross- activity of L-carbamoylase towards respective substrates for L-aminoac ylase supports the hypothesis of a common ancestor for both amino acid amidohydrolase genes.