STEREOSELECTIVE METHODOLOGY FOR 1-ARYL-1-ALKYL EPOXIDES VIA CHROMIUM TRICARBONYL COMPLEXES

Authors
DAVIES SG LOVERIDGE T CLOUGH JM
Citation
Sg. Davies et al., STEREOSELECTIVE METHODOLOGY FOR 1-ARYL-1-ALKYL EPOXIDES VIA CHROMIUM TRICARBONYL COMPLEXES, Synlett, (1), 1997, pp. 66
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
1
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):1<66:SMF1EV>2.0.ZU;2-J
Abstract
Treatment of (1RS, SSR)-(1-phenylsulfinyl-2-valeryl benzene) chromium tricarbonyl 2 with a sulfur ylide results in a highly diastereoselecti ve epoxide formation (d.s.>96:4). Regioselective opening of the epoxid e, employing an in situ trapping protocol, allows the synthesis of a h ighly functionalised, diastereomerically pure benzylic alcohol.