DIASTEREOSELECTIVE ALKYLATION OF CHIRAL DERIVATIVES OF ACETOACETIC ACID

Authors
MORENOMANAS M SEBASTIAN RM VALLRIBERA A MOLINS E
Citation
M. Morenomanas et al., DIASTEREOSELECTIVE ALKYLATION OF CHIRAL DERIVATIVES OF ACETOACETIC ACID, Tetrahedron, 51(39), 1995, pp. 10795-10800
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
39
Year of publication
1995
Pages
10795 - 10800
Database
ISI
SICI code
0040-4020(1995)51:39<10795:DAOCDO>2.0.ZU;2-8
Abstract
N-acetoacetyl-(S)-4-benzyloxazolidin-2-one and N-acetoacetyl-(R)-borna ne-10,2-sultam are alkylated at the C-alpha of the acetoacetyl moiety with significant diastereoisomeric excesses. The diastereoisomers are in general easily separable and configurationally fairly stable.