With improvements in diagnosis and treatment, the prognosis of patient
s with systemic lupus erythematosus has generally improved in recent y
ears, and similarly the outlook for women who become pregnant in the s
etting of this disorder is far more optimistic than it once was. The r
isk of significant morbidity to both the mother and fetus still exists
, however. Beginning with preconception counseling, a careful and thor
ough approach to the care of the patient and cooperation among her var
ious health care providers optimizes the chance of a successful pregna
ncy outcome.