Infantile acute hemorrhagic edema (IAHE) is a leukocytoclastic vasculi
tis that is confined to the skin without visceral involvement. Edema a
nd purpuric lesions characterize the disease, The disorder has a drama
tic onset, with a short, benign course and spontaneous resolution with
in several weeks. The clinical similarities between IAHE and Henoch-Sh
onlein purpura have been discussed in the literature. We report three
Infants with IAHE and discuss the clinical, laboratory, and histopatho
logic features of the disease. We suggest that it should be regarded a
s a separate entity for appropriate diagnostic investigations and ther
apy.